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Why Penny Stock VYNE Therapeutics (VYNE) Is Skyrocketing Today – VYNE Therapeutics (NASDAQ:VYNE)

Why Penny Stock VYNE Therapeutics (VYNE) Is Skyrocketing Today - VYNE Therapeutics (NASDAQ:VYNE)

  • VYNE Therapeutics Inc VYNE announced that the first vitiligo patient had been dosed in a Phase 1a/b trial of VYN201, a locally administered, small molecule, pan-bromodomain and extra-terminal domain (BET) inhibitor for immuno-inflammatory diseases. 
  • The clinical trial is a first-in-human study designed to generate safety and pharmacokinetic data in healthy volunteers (Phase 1a) and provide early clinical proof-of-concept data in vitiligo patients (Phase 1b).
  • The company expects topline data for Phase 1a and Phase 1b parts of the study in the first half of 2023.
  • In the Phase 1b portion, up to 30 patients with a clinical diagnosis of non-segmental vitiligo will receive VYN201 once daily in up to three dose cohorts. 
  • The primary objective of the Phase 1b portion of the study will be to evaluate the safety and pharmacokinetics of VYN201. 
  • The exploratory efficacy of VYN201 in non-segmental vitiligo patients will also be evaluated, including pharmacodynamic biomarkers and photography.
  • In August, VYNE Therapeutics announced results from the Phase 2a segment of a Phase 1b/2 trial of FMX114 for mild-to-moderate atopic dermatitis (AD), missing the primary endpoint of the disease severity index.
  • Price Action: VYNE shares are up 56.6% at $0.30 on the last check Tuesday.

Written by biedex markets